creb inhibitor (MedChemExpress)
Structured Review

Creb Inhibitor, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 93 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/creb+inhibitor/666-15/pmc13376770-310-26-29
Average 95 stars, based on 93 article reviews
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1) Product Images from "Catecholaminergic neurons boost fibroblast osteogenic activity in keloid"
Article Title: Catecholaminergic neurons boost fibroblast osteogenic activity in keloid
Journal: Nature Communications
doi: 10.1038/s41467-026-72823-9
Figure Legend Snippet: a cAMP quantitation of keloid fibroblasts treated or not with epinephrine in the presence or absence of metoprolol for 30 min ( n = 2 biologically independent samples for fibroblasts treated with epinephrine in the presence of metoprolol, and n = 3 biologically independent samples for other groups). b qPCR analysis of TSN expression in keloid fibroblasts treated or not with epinephrine in the presence or absence of PKA inhibitor or CREB inhibitor for 6 h ( n = 4 biologically independent samples for fibroblasts treated with epinephrine in the presence of CREB inhibitor, and n = 5 biologically independent samples for other groups). c Immunoblotting and quantitative analysis of IBSP and TSN expression in keloid fibroblasts treated or not with epinephrine in the presence or absence of PKA inhibitor or CREB inhibitor for 24 h ( n = 3 biologically independent samples). d qPCR analysis of the abundance of the TSN promoter that immunoprecipitated with αCREB1 or IgG control in keloid fibroblasts treated or not with epinephrine in the presence or absence of metoprolol for 30 min ( n = 6 biologically independent samples for Epinephrine-CREB1 and Epinephrine & Metoprolol-CREB1, and n = 5 biologically independent samples for other groups). Data are presented as the percentages of αCREB1- or IgG-pulled TSN promoter relative to that in the input. Data represent the mean ± SD; p -values were determined by one-way ANOVA. Data are representative of at least 2 independent experiments.
Techniques Used: Quantitation Assay, Expressing, Western Blot, Immunoprecipitation, Control
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